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引用文献

Nature 2011 Mar 10; 471 (7337): 216-9.

Human-Specific Loss of Regulatory DNA and the Evolution of Human-Specific Traits.

Abstract:
Humans differ from other animals in many aspects of anatomy, physiology, and behaviour; however, the genotypic basis of most human-specific traits remains unknown1. Recent whole-genome comparisons have made it possible ... more

Dev Cell. 21: 627 (2011)

A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial.

Abstract:
Morphogenes is of mammalian facial processes requires coor dination of cellular proliferation, migration, and apoptos is to develop intricate features. Cleft lip and/ or palate (CL/P ), the most frequent ... more

PLoS Biol. 9: e1001188 (2011)

De Novo Genesis of Enhancers in Vertebrates.

Abstract:
Evolutionary innovation relies partially on changes in gene regulation. While a growing body of evidence demonstrates that such innovation is generated by functional changes or translocation of regulatory elements via ... more
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